Recombinant Human CD47 Protein

    • Recombinant Human CD47 Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Human CD47 Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Human CD47 Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSH030305

      Synonyms:IAP;MER6;OA3

      Size:
      • 50 µg
      • 100 µg
      Qty:
      - +
      Price: $454

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms IAP;MER6;OA3
      Species Human
      Expression_host HEK293 Cells
      Sequence Met 1-Pro 139
      Accession NP_942088.1
      Mol_Mass 14.5 kDa
      Bio_Activity Measured by its ability to bind human SIRPA-His in functional ELISA. Measured by its ability to bind mouse SIRPA-His(Cat: PKSM040419)in functional ELISA.

      Properties

      Purity > 90 % as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per µg as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile PBS, pH 7.4
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.

      SDS-PAGE

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