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Recombinant Human CDH1 Protein (His Tag)

Uniprot : P12830-1
  • Cat.No.:PKSH500014

  • Expression host: E.coli

To Purchase PKSH500014

Size:
  • 20µg
  • 100µg
Price: $99
Qty:

Description

Synonyms Arc 1,CADH1,Cadherin 1,cadherin 1 type 1 E-cadherin,Cadherin1,CAM 120/80,CD 324,CD324,CD324 antigen,cdh1,CDHE,E-Cad/CTF3,E-cadherin,ECAD,Epithelial cadherin,epithelial calcium dependant adhesion protein,LCAM,Liver cell adhesion molecule,UVO,Uvomorulin
Species Human
Expression_host E.coli
Sequence Asp155-Phe375
Accession P12830-1
Application Immunogen(E-AB-40285)
Mol_Mass 23.9kDa
AP_Mol_Mass 35kDa
Tag N-His

Properties

Purity >85 % as determined by reducing SDS-PAGE.
Endotoxin level No data available.
Storage Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Formulation Lyophilized from sterile PBS, pH 7.4
Reconstitution Please refer to the printed manual for detailed information.

Background

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

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