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Cat.No.:PKSH031819
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Synonyms | Macrophage colony-stimulating factor 1 receptor;CSF-1 receptor;CSF-1-R;CSF-1R;M-CSF-R;Proto-oncogene c-Fms;CD115;CSF1R;FMS;C-FMS;FIM2;FMS;HDLS;M-CSF-R;MCSF Receptor |
Species | Human |
Expression_host | HEK293 Cells |
Sequence | Met 1-Glu512 |
Accession | NP_005202.2 |
Application | Functional ELISA |
Mol_Mass | 56.0 kDa |
AP_Mol_Mass | 85-95 kDa |
Tag | C-His |
Bio_Activity | 1. Immobilized human CSF1R at 10 μg/mL (100 μl/well) can bind biotinylated human CSF-1, The EC50 of biotinylated human CSF-1 is 8 ng/mL. 2. Measured by its ability to inhibit the human CSF-induced proliferation of M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 6-30 μg/mL in the presence of 3 ng/ml Recombinant Human M-CSF. |
Purity | > 98 % as determined by reducing SDS-PAGE. |
Endotoxin level | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from sterile PBS, pH 7.4 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |