Recombinant Human CSNK1A1 / CKI-alpha / CK1 Protein (GST tag)

    • Recombinant Human CSNK1A1 / CKI-alpha / CK1 Protein (GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Human CSNK1A1 / CKI-alpha / CK1 Protein (GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Human CSNK1A1 / CKI-alpha / CK1 Protein (GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSH030400

      Synonyms:CK1;CK1a;CKIa;HEL-S-77p;HLCDGP1;PRO2975

      Size:
      • 20 µg
      • 50 µg
      Qty:
      - +
      Price: $486

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms CK1;CK1a;CKIa;HEL-S-77p;HLCDGP1;PRO2975
      Species Human
      Expression_host Baculovirus-Insect Cells
      Sequence Met 1-Phe 337
      Accession P48729-1
      Mol_Mass 65.2 kDa
      AP_Mol_Mass 62 kDa
      Tag N-GST
      Bio_Activity The specific activity was determined to be 30 nmol/min/mg using casein as substrate.

      Properties

      Purity > 90 % as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per µg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as sterile 20mM Tris, 500mM NaCl, 2mM GSH, pH 7.4
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. High expression of CSNK2A1, or concomitantly high expression of CSNK2A1, are independent prognostic factors of poor survival in NSCLC patients. CSNK2A1 are useful prognosis markers in non-small cell lung cancer (NSCLC) patients after complete resection, independent of lymph node metastasis status. CSNK1A1 can phosphorylate a large number of proteins. It participates in Wnt signaling. It phosphorylates CTNNB1 at 'Ser-45'. CSNK1A1 may play a role in segregating chromosomes during mitosis.

      SDS-PAGE

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      MSDS for ELISA

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