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Recombinant Human Cyclophilin B/PPIB Protein (His Tag)

  • Cat.No.:PKSH033569

  • Expression host: Human Cells

To Purchase PKSH033569

Size:
  • 10μg
  • 50μg
Price: $111
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Description

Synonyms CYP-S1; CYPB; HEL-S-39; OI9; SCYLP
Species Human
Expression_host Human Cells
Sequence Asp34-Ala212
Accession P23284
Mol_Mass 20.9 kDa
AP_Mol_Mass 21 kDa
Tag C-His

Properties

Purity > 95% as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg as determined by the LAL method.
Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4.
Reconstitution Please refer to the printed manual for detailed information.

Background

Cyclophilin B (SCYLP, CyPB and peptidyl-prolyl cis-trans isomerase B) is a 24 kDa glycoprotein member of the B subfamily of the cyclophilin-type PPIase family of molecules. It is both secreted and retained in the ER. When secreted, Cyclophilin B mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization, and facilitating the activity of additional chaperones.

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