Recombinant Human ERN1 / IRE1 Protein (aa 465-977, His & GST tag)

    • Recombinant Human ERN1 / IRE1 Protein (aa 465-977, His & GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    <
    >
    • Recombinant Human ERN1 / IRE1 Protein (aa 465-977, His & GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Human ERN1 / IRE1 Protein (aa 465-977, His & GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSH030346

      Synonyms:hIRE1p;IRE1;IRE1a;IRE1P

      Size:
      • 20µg
      • 50µg
      Qty:
      - +
      Price: $486

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms hIRE1p;IRE1;IRE1a;IRE1P
      Species Human
      Expression_host Baculovirus-Insect Cells
      Sequence Pro 465-Leu 977
      Accession O75460-1
      Mol_Mass 86 kDa
      AP_Mol_Mass 90 kDa
      Tag N-His & GST
      Bio_Activity 1.Kinase activity untested 2. The specific activity was determined to be 5 nmol/min/mg using MBP as substrate

      Properties

      Purity > 80 % as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per µg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as sterile 20mM Tris, 500mM NaCl, 10% gly, pH 7.4
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      The encoded protein contains two functional catalytic domains, a serine/threonine-protein kinase domain and an endoribonuclease domain. This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR). The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins, regulating protein synthesis and activating molecular chaperones. This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1.

      SDS-PAGE

      • Show all (0)
      • Reviews (0)
      • Q&A (0)
      ... Show All Show Less
      MSDS for ELISA

      Browsing History


        People Also Bought