Recombinant Human FGL1 Protein (His Tag)(Active)

    • Recombinant Human Fibrinogen-like protein 1 / FGL-1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human Fibrinogen-like protein 1 / FGL-1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human Fibrinogen-like protein 1 / FGL-1 Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033680

      Synonyms:Fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $328

      Lead Time: Order now, ship in 3 daysWelcome to order from local distributors.

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      Overview

      Synonyms Fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1
      Species Human
      Expression_host Human Cells
      Sequence Leu23-Ile312
      Accession Q08830
      Application Functional ELISA
      Mol_Mass 35 kDa
      AP_Mol_Mass 35 kDa
      Tag C-His
      Bio_Activity Immobilized Human FGL1-His at 5μg/ml(100 μl/well) can bind Human LAG-3-Fc(Cat: PKSH033597). The ED50 of Human FGL1-His is 0.059μg/mL.

      Properties

      Purity > 90% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris,300mM NaCl, 10% Glycerol,2mMEDTA,pH 8.0.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Hepassocin, also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1), is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.

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