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Recombinant Human IL17RC Protein (aa 1-454, His Tag)

Uniprot : Q8NAC3

Cat.No.:PKSH031012
Expression host: Baculovirus-Insect Cells

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100μg

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Description

Synonyms	IL17-RL;IL17RL;UNQ6118/PRO20040/PRO38901
Species	Human
Expression_host	Baculovirus-Insect Cells
Sequence	Met 1-Ala 454
Accession	NP_116121.2
Application	Functional ELISA
Mol_Mass	49.6 kDa
AP_Mol_Mass	60 kDa
Tag	C-His
Bio_Activity	Measured by its ability to bind with recombinant human IL17A-His in a functional ELISA. Measured by its ability to bind with recombinant human 17A in a functional ELISA.

Properties

Purity	> 90 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% glycerol Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

The hypomethylation within the IL17RC gene promoter in peripheral blood is not suitable for use as a clinical biomarker of AMD. This study highlights the need for considerable replication of epigenetic association studies prior to clinical application. methylation of IL17RC could play as a marker in choroidal neovascularization (CNV) and degeneration of retinal pigment epithelium (RPE) cells in vitro.

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