English Toll-free:1-888-852-8623 or Contact Us
Keyword cannot be empty !

Recombinant Human IL1RL1/ST2 Protein (His Tag)

Cat:PKSH031874
Manual MSDS

Price: $ 486

Size:
100μg
Quantity:
  • Expression Host: HEK293 Cells
  • Accession: NP_003847.2
  • Applications: ELISA
Add to cart

For research use only. Order now, ship in 3 days

Product Details
Synonyms DER4;FIT-1;IL1RL1;IL33R;IL-1 R4;ST2;ST2L;ST2V;T1
Species Human
Expression Host HEK293 Cells
Sequence Met 1-Phe 328
Accession NP_003847.2
Calculated Molecular Weight 36.5 kDa
Observed Molecular Weight 55-60 kDa
Tag C-His
Bio-activity Immobilized recombinant human IL33 at 10 μg/mL (100 μl/well) can bind biotinylated human IL1RL1 with a linear range of 0.16-8 μg/ml.
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background IL-1 receptor&ndash;like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interlukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described, and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage pro-inflammatory function. IL33 is a specific ligand of ST2L and induces production of Th2 cytokines.