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Recombinant Human IL2RG/CD132 Protein (aa 23-262, Fc Tag)

Uniprot : P31785

Cat.No.:PKSH033410
Expression host: HEK293 Cells

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Description

Synonyms	Cytokine receptor common subunit gamma;Interleukin-2 receptor subunit gamma;gammaC;P64;CD132;IL2RG;SCIDX;SCIDX1;CIDX
Species	Human
Expression_host	HEK293 Cells
Sequence	Leu23-Ala262
Accession	P31785
Mol_Mass	55.4 kDa
AP_Mol_Mass	85-100 kDa
Tag	C-Fc

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

IL2RG contains one fibronectin type-III domain. IL2RG is an important signaling component of many interleukin receptors; including those of interleukin -2; -4; -7 and -21; and is thus referred to as the common gamma chain. IL2RG interacts with SHB upon interleukin stimulation and HTLV-1 accessory protein p12I. Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID) and severe combined immunodeficiency X-linked T-cell-negative /B-cell-positive / NK-cell-negative (XSCID).

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