Recombinant Human IL7 / interleukin 7 Protein

    • Recombinant Human IL7 / interleukin 7 Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Human IL7 / interleukin 7 Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Human IL7 / interleukin 7 Protein-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSH030436

      Synonyms:IL-7;Interleukin-7

      Size:
      • 10 µg
      • 20 µg
      Qty:
      - +
      Price: $281

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms IL-7;Interleukin-7
      Species Human
      Expression_host E.coli
      Sequence Asp26-His177
      Accession NP_000871.1
      Mol_Mass 17.5 kDa
      AP_Mol_Mass 19 kDa
      Bio_Activity Measured by its binding ability in a functional ELISA.Immobilized human IL7 at 10 μg/ml (100 μl/well) can bind human IL7Ra-Fch, The EC50 of human IL7Ra-Fch is 15.2-35.6 ng/ml.2. Measured in a cell proliferation assay using antibody against CD3-activated human peripheral blood lymphocytes (PBL). The ED50 for this effect is typically 1-10 ng/ml.

      Properties

      Purity > 90 % as determined by reducing SDS-PAGE.
      Endotoxin Please contact us for more information.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile 25mM NaH2PO4, 400mM NaCl, pH 6.8
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      IL7, also known as interleukin 7, is a hematopoietic growth factor which belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes.

      SDS-PAGE

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