Current Position:Home>>Protein Products>>Recombinant Proteins>> Recombinant Human IL-23 Recetor/IL-23R Protein (His Tag)

Recombinant Human IL-23 Recetor/IL-23R Protein (His Tag)

Uniprot : Q5VWK5

Cat.No.:PKSH032578
Expression host: HEK293 Cells

Filter:

To Purchase PKSH032578

Size:

10μg
50μg

Price: $117

Qty:

Welcome to order from local distributors.

FAQs for Recombinant Proteins

Have Questions?

Add to cart Bulk request

For research use only. Order now, ship in 3 days

Description

Synonyms	Interleukin-23 receptor;IL23R;IL-23 receptor;IL-23R
Species	Human
Expression_host	HEK293 Cells
Sequence	Gly24-Asp353
Accession	AAM44229.1
Mol_Mass	38.7 kDa
AP_Mol_Mass	50-90 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Interleukin 23 receptor (IL23R) is a type I cytokine receptor for IL23. IL23 receptor complex is comprised of two subunits; the IL12Rβ1 subunit; which is shared with several cytokines; and a subunit that is unique to IL-23. IL23; after binding to IL23R; activates memory T cells and mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17 lymphocytes. IL23R is expressed on T cells; NK cells; dendritic cells; and macrophages. In fact; polymorphisms of the IL23R gene were reported to be associated with susceptibility to inflammatory diseases and autoimmune diseases such as psoriasis; multiple sclerosis; Graves's ophtalmopathy and inflammatory bowel diseases. The IL23R is known to be critically involved in the carcinogenesis of different malignant tumor.

Related Products

Proteins

Citations

Reviews/Q&A

Show all
Reviews
Q&A

... Show All Show Less

*Product Name:
*Catalog Number:
*Name:
*Email:
*Message:
*Country:
*When will you use it?	Within 1 month In 2 to 3 month In 4 to 6 month 6 months later
*Captcha:	Click to load Captcha