Recombinant Human LAG3 Protein (Fc Tag)

    • Recombinant Human LAG3 Protein (Fc Tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Human LAG3 Protein (Fc Tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Human LAG3 Protein (Fc Tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSH030460

      Synonyms:CD223;LAG-3

      Size:
      • 50 µg
      • 200 µg
      Qty:
      - +
      Price: $454

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CD223;LAG-3
      Species Human
      Expression_host HEK293 Cells
      Sequence Met 1-Leu450
      Accession NP_002277.4
      Mol_Mass 72.3 kDa
      Tag C-Fc

      Properties

      Purity > (3.0+91.0+3.1) % as determined by reducing SDS-PAGE..
      Endotoxin < 1.0 EU per µg of the protein as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile PBS, pH 7.4
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells. It also acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signalling, leading to increased antigen-specific T-cell responses in vivo.

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      MSDS for ELISA

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