Recombinant Human LILRA5 Protein (His Tag)

    • Recombinant Human LILRA5 / CD85f Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human LILRA5 / CD85f Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human LILRA5 / CD85f Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033605

      Synonyms:Leukocyte immunoglobulin-like receptor subfamily A member 5; CD85 antigen-like family member F; Immunoglobulin-like transcript 11; ILT-11; Leukocyte immunoglobulin-like receptor 9; LIR-9; CD85f; LILRA5; LILRB7;CD85F;ILT11;LILRB7;LIR-9;LIR9

      Size:
      • 10μg
      • 50μg
      Qty:
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      Price: $92

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      Overview

      Synonyms Leukocyte immunoglobulin-like receptor subfamily A member 5; CD85 antigen-like family member F; Immunoglobulin-like transcript 11; ILT-11; Leukocyte immunoglobulin-like receptor 9; LIR-9; CD85f; LILRA5; LILRB7;CD85F;ILT11;LILRB7;LIR-9;LIR9
      Species Human
      Expression_host Human Cells
      Sequence Gly42-Arg268
      Accession A6NI73
      Mol_Mass 26.1 kDa
      AP_Mol_Mass 35-40 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Leukocyte Immunoglobulin-like Receptor Subfamily A Member 5(LILRA5)is a member of the leukocyte immunoglobulin-like receptors (LILR), comprise a family of activating and inhibitory type immunoreceptors. LILRA5 consists of a 227 amino acid (aa) extracellular domain (ECD), a 21 aa transmembrane segment, and a 10 aa cytoplasmic tail. The ECD contains two Ig-like domains and the transmembrane segment contains a positively charged aspartic acid residue which may mediate its association with the signaling molecule, FcR common gamma chain. LILRA5 is expressed by monocytes, macrophages, and neutrophils. Cross-linking of LILRA5 on monocytes induces the expression of pro-inflammatory cytokines (IL-1beta, IL-6, TNF-alpha) as well as the anti-inflammatory IL-10. It can be detected in tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses.

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      MSDS for ELISA ISO 9001

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