Recombinant Human OSMR/IL31RB Protein (aa 28-739, His Tag)
Price: $ 261
Price: $ 98
Size:
50μg
10μg
Quantity:
- Expression Host: HEK293 Cells
- Accession: Q99650
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Product Details
Synonyms | Oncostatin-M-Specific Receptor Subunit Beta;Interleukin-31 Receptor Subunit Beta;IL-31 Receptor Subunit Beta;IL-31R Subunit Beta;IL-31R-Beta;IL-31RB;OSMR;OSMRB;PLCA1 |
Species | Human |
Expression Host | HEK293 Cells |
Sequence | Glu28-Ser739 |
Accession | Q99650 |
Calculated Molecular Weight | 82.0 kDa |
Observed Molecular Weight | 132 kDa |
Tag | C-His |
Purity | > 90 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background | Oncostatin-M-Specific Receptor Subunit β (OSMRβ) is a 150 - 180 kDa member of the IL-6 receptor family. OSMRβ associates with gp130 to form the type II OSM receptor, the receptor is responsive to OSM. Gp130 subunit is shared by other IL-6 family cytokine receptors, and OSMRβ associates with gp130-like receptor (GPL) to form a receptor complex responsive to IL-31. The human OSMRβ cDNA encodes a 979 amino acid (aa) precursor, the precursor includes a 27 aa signal sequence, a 712 aa extracellular domain (ECD), a 22 aatransmembrane segment, and a 218 aa cytoplasmic domain. The ECD contains one partial and one complete hematopoietin domain, an Ig-like domain, and three Fibronectin type-III domains. |