Recombinant Human TAOK3 / JIK / MAP3K18 Protein (aa 1-411, His & GST tag)

    • Recombinant Human TAOK3 / JIK / MAP3K18 Protein (aa 1-411, His & GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Human TAOK3 / JIK / MAP3K18 Protein (aa 1-411, His & GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Human TAOK3 / JIK / MAP3K18 Protein (aa 1-411, His & GST tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSH030364

      Synonyms:DPK;JIK;MAP3K18

      Size:
      • 20μg
      • 50μg
      Qty:
      - +
      Price: $486

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms DPK;JIK;MAP3K18
      Species Human
      Expression_host Baculovirus-Insect Cells
      Sequence Met 1-Asp 411
      Accession Q9H2K8-1
      Mol_Mass 74.3 kDa
      AP_Mol_Mass 85 kDa
      Tag N-His & GST
      Bio_Activity The specific activity was determined to be 10 nmol/min/mg using synthetic PKCtide peptide (ERMRPRKRQGSVRRRV) as substrate.

      Properties

      Purity > 92 % as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per µg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as sterile 20mM Tris, 500mM NaCl, 3mM GSH, pH 7.4, 10% gly
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, Thousand and one amino acid protein 3, JIK, TAOK3 and MAP3K18, is cytoplasm and peripheral membrane protein which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. Protein kinases are pivotal regulators of cell signaling that modulate each other's functions and activities through site-specific phosphorylation events. TAOK3 / JIK contains one protein kinase domain. TAOK3 / JIK is ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver. TAOK3 / JIK inhibits the basal activity of Jun kinase. It is negatively regulated by epidermal growth factor (EGF). When overexpressed, TAOK3 / JIK may activate ERK1 / ERK2 and JNK / SAPK.

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