Recombinant Human Troponin C/TNNC1 Protein (His Tag)

    • Recombinant Human Troponin C / TNNC1 Protein (N-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human Troponin C / TNNC1 Protein (N-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human Troponin C / TNNC1 Protein (N-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033520

      Synonyms:CMD1Z;CMH13;TN-C;TNC;TNNC

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $257

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      Overview

      Synonyms CMD1Z;CMH13;TN-C;TNC;TNNC
      Species Human
      Expression_host E.coli
      Sequence Met1-Glu161
      Accession P63316
      Mol_Mass 19.8 kDa
      AP_Mol_Mass 17-20 kDa
      Tag N-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice.Upon receipt, store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris,100mM NaCl,1mM DTT,10% glycerol,pH8.0.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Troponin I, also known as TNI, is a 24 kDa component of a protein complex on striated muscle thin filaments.Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Troponin I inhibits the calcium-dependent muscle contraction mediated by Troponins C and T. The expression of cardiac Troponin I (TNNI3) is restricted to cardiac muscle, while TNNI1 and TNNI2(encoded by distinct genes) are expressed in skeletal muscle. Mutations of cardiac Troponin I are associated with heriditary cardiomyopathy. Human cardiac Troponin I shares 93% amino acid sequence identity with mouse and rat cardiac Troponin I.

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      MSDS for ELISA ISO 9001

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