Recombinant Human VEGF-B/VEGFB Protein (Fc Tag)

    • Recombinant Human VEGFB Protein (N-Fc)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human VEGFB Protein (N-Fc)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human VEGFB Protein (N-Fc)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033474

      Synonyms:Vascular endothelial growth factor B;VEGF-B;VEGF-related factor;VRF

      Size:
      • 10μg
      • 50μg
      Qty:
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      Price: $129

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      Overview

      Synonyms Vascular endothelial growth factor B;VEGF-B;VEGF-related factor;VRF
      Species Human
      Expression_host Human Cells
      Sequence Pro22-Ala207
      Accession P49765
      Mol_Mass 45.7 kDa
      AP_Mol_Mass 40&60 kDa
      Tag N-Fc

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      VEGFB, as known as VRF, is a member of the VEGF family of growth factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane receptor for semaphorins/collapsins, ligands involved in neuron guidance.

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