Current Position:Home>>Protein Products>>Recombinant Proteins>> Recombinant Mouse GITR/TNFRSF18 Protein (Fc & His Tag)

Recombinant Mouse GITR/TNFRSF18 Protein (Fc & His Tag)

Uniprot : O35714

Cat.No.:PKSM041029
Expression host: HEK293 Cells

Filter:

To Purchase PKSM041029

Size:

10μg
50μg

Price: $111

Qty:

Welcome to order from local distributors.

FAQs for Recombinant Proteins

Have Questions?

Add to cart Bulk request

For research use only. Order now, ship in 3 days

Description

Synonyms	Tumor necrosis factor receptor superfamily member 18;Glucocorticoid-induced TNFR-related protein;Tnfrsf18;AITR;CD357;GITR-D;TNFRSF18
Species	Mouse
Expression_host	HEK293 Cells
Sequence	Ser22-His153
Accession	O35714
Application	Functional ELISA
Mol_Mass	42.3 kDa
AP_Mol_Mass	60 kDa
Tag	C-Fc-His

Properties

Purity	> 90 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution	Please refer to the printed manual for detailed information.

Background

Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6 and binds through its C-terminus to SIVA1/SIVA.It preferentially expressed in activated T lymphocytes and up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation.

Related Products

Proteins

Citations

Reviews/Q&A

Show all
Reviews
Q&A

... Show All Show Less

*Product Name:
*Catalog Number:
*Name:
*Email:
*Message:
*Country:
*When will you use it?	Within 1 month In 2 to 3 month In 4 to 6 month 6 months later
*Captcha:	Click to load Captcha