SPHK2 Polyclonal Antibody

Uniprot : Q9NRA0
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14745

      Synonyms:SK 2,Sphingosine kinase 2,Sphingosine kinase type 2,SPHK2,SPHK2,SPK 2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms SK 2,Sphingosine kinase 2,Sphingosine kinase type 2,SPHK2,SPHK2,SPK 2
      Swissprot Q9NRA0
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human SPHK2
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:200-1:1000, IHC 1:100-1:300
      Concentration 0.6 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Membrane and Lysosome membrane.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. 

      Images

      Western Blot analysis of Mouse liver tissue using SPHK2 Polyclonal Antibody at dilution of 1:200

      Immunohistochemistry of paraffin-embedded Human colon cancer using SPHK2 Polyclonal Antibody at dilution of 1:80

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using SPHK2 Polyclonal Antibody at dilution of 1:80

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