STK4 Polyclonal Antibody

Uniprot : Q13043
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-40157

      Synonyms:Antigen NY-CO-13,BCC7,Cellular tumor antigen p53,FLJ92943,LFS1,Mutant tumor protein 53,p53,p53 tumor suppressor,P53,Phosphoprotein p53,Tp53,Transformation related protein 53,TRP53,Tumor protein 53,Tumor protein p53,Tumor suppressor p53

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,R

      Applications: WB,IHC

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Antigen NY-CO-13,BCC7,Cellular tumor antigen p53,FLJ92943,LFS1,Mutant tumor protein 53,p53,p53 tumor suppressor,P53,Phosphoprotein p53,Tp53,Transformation related protein 53,TRP53,Tumor protein 53,Tumor protein p53,Tumor suppressor p53
      Swissprot Q13043
      Source Rabbit
      Reactivity Human,Rat
      Immunogen Recombinant human Serine/threonine-protein kinase 4 protein
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R217)
      Recommended dilution WB 1:500-1:1000, IHC 1:50-1:100
      Concentration 2mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Nucleus. The caspase-cleaved form cycles between the nucleus and cytoplasm.
      Tissue specificity Ubiquitously expressed.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
      Background The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

      Images

      polyclonal antibody-Elabscience

      Western Blot analysis of 293T and Rat liver using STK4 Polyclonal Antibody at dilution of 1:600

      polyclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Rat lung using STK4 Polyclonal Antibody at dilution of 1:50

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