TNF alpha Polyclonal Antibody

Uniprot : P01375
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14408

      Synonyms:APC1,APC1 protein,Cachectin,DIF,Differentiation inducing factor,Macrophage cytotoxic factor,Tnf,TNF superfamily,member 2,TNF,macrophage derived,TNF,monocyte derived,TNF-a,TNF-alpha,TNFA,TNFA,TNFSF2,Tumor necrosis factor alpha,Tumor necrosis factor,Tumor necrosis factor ligand superfamily member 2,Tumor Necrosis Factor,Membrane Form,Tumor necrosis factor,soluble form

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms APC1,APC1 protein,Cachectin,DIF,Differentiation inducing factor,Macrophage cytotoxic factor,Tnf,TNF superfamily,member 2,TNF,macrophage derived,TNF,monocyte derived,TNF-a,TNF-alpha,TNFA,TNFA,TNFSF2,Tumor necrosis factor alpha,Tumor necrosis factor,Tumor necrosis factor ligand superfamily member 2,Tumor Necrosis Factor,Membrane Form,Tumor necrosis factor,soluble form
      Swissprot P01375
      Source Rabbit
      Reactivity Human
      Immunogen Recombinant protein of human TNF
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:25-1:100
      Concentration 0.2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted and Cell membrane.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

      Images

      Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TNF alpha Polyclonal Antibody at dilution 1:35

      Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TNF alpha Polyclonal Antibody at dilution 1:35

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