TNNI2 Polyclonal Antibody

Uniprot : P48788
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      Catalog number:E-AB-62946

      Synonyms:AMCD 2B,AMCD2B,DA 2B,DA2B,fast skeletal muscle,Fast twitch skeletal muscle troponin I,fast-twitch isoform,FSSV,fsTnI,TNNI 2,Tnni2,TNNI2,tro,Troponin I,Troponin I fast skeletal muscle,Troponin I fast twitch 2,Troponin I fast twitch isoform,Troponin I fast twitch skeletal muscle isoform,Troponin I skeletal fast,Troponin I type 2 (skeletal fast),Troponin I type 2

      Size:
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $129

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms AMCD 2B,AMCD2B,DA 2B,DA2B,fast skeletal muscle,Fast twitch skeletal muscle troponin I,fast-twitch isoform,FSSV,fsTnI,TNNI 2,Tnni2,TNNI2,tro,Troponin I,Troponin I fast skeletal muscle,Troponin I fast twitch 2,Troponin I fast twitch isoform,Troponin I fast twitch skeletal muscle isoform,Troponin I skeletal fast,Troponin I type 2 (skeletal fast),Troponin I type 2
      Swissprot P48788
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human TNNI2
      Application WB(Detection kit: E-IR-R304)
      Recommended dilution WB 1:500 - 1:2000
      Concentration 1mg/ml
      Clonality Polyclonal

      Properties

      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
      Background This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

      Images

      Western blot analysis of extracts of various cell lines with TNNI2 Polyclonal Antibody

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