TTR Monoclonal Antibody

Uniprot : P02766
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    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
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    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience

      Catalog number:E-AB-22255

      Synonyms:Amyloid polyneuropathy,Amyloidosis I,ATTR,Carpal tunnel syndrome 1,CTS,CTS1,Dysprealbuminemic euthyroidal hyperthyroxinemia,Dystransthyretinemic hyperthyroxinemia,Epididymis luminal protein 111,HEL111,HsT2651,PALB,Prealbumin amyloidosis type I,Prealbumin,Prealbumin Thyroxine-binding,Senile systemic amyloidosis,TBPA,Thyroxine binding prealbumin,Transthyretin,TTHY,TTR,TTR protein

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Mouse

      Reactivity: H

      Applications: WB,IHC-p

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Amyloid polyneuropathy,Amyloidosis I,ATTR,Carpal tunnel syndrome 1,CTS,CTS1,Dysprealbuminemic euthyroidal hyperthyroxinemia,Dystransthyretinemic hyperthyroxinemia,Epididymis luminal protein 111,HEL111,HsT2651,PALB,Prealbumin amyloidosis type I,Prealbumin,Prealbumin Thyroxine-binding,Senile systemic amyloidosis,TBPA,Thyroxine binding prealbumin,Transthyretin,TTHY,TTR,TTR protein
      Swissprot P02766
      Source Mouse
      Reactivity Human
      Immunogen Recombinant Protein of TTR
      Application WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R217)
      Recommended dilution WB 1:500-2000, IHC 1:50-300
      Concentration 1 mg/mL
      Clonality Monoclonal

      Properties

      Cellular localization Secreted. Cytoplasm.
      Tissue specificity Detected in serum and cerebrospinal fluid (at protein level). Highly expressed in choroid plexus epithelial cells. Detected in retina pigment epithelium and liver.
      Clone No. Clone:3F2
      Isotype IgG
      Purification Protein A purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
      Background This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

      Images

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      Western Blot analysis of Human serum using TTR Monoclonal Antibody at dilution of 1:2000.

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      Immunohistochemistry of paraffin-embedded Human Thyroid tissue using TTR Monoclonal Antibody at dilution of 1:200.

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      MSDS for ELISA ISO 9001

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