WNT6 Polyclonal Antibody

Uniprot : Q9Y6F9
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-17612

      Synonyms:Protein Wnt 6,Protein Wnt-6,Protein Wnt-6 precursor,Wingless type MMTV integration site family,member 6,wnt 6,Wnt6

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Protein Wnt 6,Protein Wnt-6,Protein Wnt-6 precursor,Wingless type MMTV integration site family,member 6,wnt 6,Wnt6
      Swissprot Q9Y6F9
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthetic peptide of human WNT6
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:25-100, ELISA 1:2000-5000
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted>extracellular space>extracellular matrix.
      Tissue specificity Expressed in gastric cancer cell lines and gastric cancer tissues (at protein level). Detected in the apical gland region of the gastric foveolar epithelium (at protein level).1 Publication
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using WNT6 Polyclonal Antibody at dilution 1:35

      Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using WNT6 Polyclonal Antibody at dilution 1:35

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