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For research use only.
Verified Samples |
Verified Samples in IHC: Human lung cancer, Human liver cancer, Human colon carcinoma, Human breast cancer, Human gastric cancer |
Dilution | IHC 1:50-1:100 |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein of human ATG7 (NP_001129503.2). |
Synonyms | APG7-LIKE, APG7L, ATG7, Apg7/Atg7, GSA7 |
Swissprot | |
Cellular Localization | Cytoplasm. Preautophagosomal structure. Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme. |
Concentration | 1 mg/mL |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. |
Other Clones
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Unconjugated
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