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100μg $ 82.00
25μg $ 36.00
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For research use only.

Alternate Names B7H1PD-L1PDCD1L1PDCD1LG1PDL1,  B7 homolog 1,  B7-H,  B7-H1,  Programmed cell death ligand 1
Clone No
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Background CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
Abbre CD274;PD-L1
Swissprot
Host Rat
Reactivity Mouse
Clonality Monoclonal
Isotype Rat IgG2b, κ
Isotype Control E-AB-F09843B
Applications
FCM
Research Areas Cancer Biomarkers;Costimulatory Molecules;Immunology
Cellular Localization
Membrane
Form Liquid
Concentration
0.5 mg/mL
Conjugation Biotin
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage This product can be stored at 2-8°C for 12 months. Do not freeze.
Expiration Date 12 months
Shipping Ice bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

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APC

Biotin

Elab Fluor®488

Elab Fluor®647

FITC

PE

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