DEFA1 Polyclonal Antibody (E-AB-12365)
For research use only.
| Verified Samples |
Verified Samples in WB: Human lung |
| Dilution | WB 1:500-1:1000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human DEFA1 |
| Abbre | DEFA1 |
| Synonyms | DEF1, DEF3, DEFA1, DEFA2, DEFA3, Defensin alpha 1, Defensin alpha 2, Defensin alpha 3, HNP1, HNP3, HP1, HP3, MRS, Neutrophil defensin 1, Neutrophil defensin 2, Neutrophil defensin 3 |
| Swissprot | |
| Calculated MW | 10 kDa |
| Cellular Localization | Secreted |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Immunology, Microbiology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. |
Other Clones
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Other Formats
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Unconjugated
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