EIF4G1 Polyclonal Antibody (E-AB-16401)
For research use only.
| Verified Samples |
Verified Samples in WB: LoVo, 293T Verified Samples in IHC: Human thyroid cancer, Human gastric cancer |
| Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human EIF4G1 |
| Abbre | EIF4G1 |
| Synonyms | DKFZp686A1451, EIF4 gamma, EIF4F, EIF4G, EIF4G1, EIF4GI, Eukaryotic translation initiation factor 4 gamma 1, IF4G1, eIF 4 gamma 1, eIF 4G 1, eIF 4G1, eIF-4-gamma 1, eIF-4G 1, eIF-4G1, p220 |
| Swissprot | |
| Calculated MW | 175 kDa |
| Cellular Localization | Cytosol, Nucleus, Other locations: cytoplasm, eukaryotic translation initiation factor 4F complex, membrane, polysome. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F.This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis.The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex.The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex.A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation.Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. |
Other Clones
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Other Formats
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Unconjugated
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