GMFG Polyclonal Antibody (E-AB-10913)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse heart, Human fetal brain Verified Samples in IHC: Human cervical cancer, Human colon cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human GMFG |
| Abbre | GMFG |
| Synonyms | GMF GAMMA, GMF-gamma, GMFG, Glia maturation factor, Glia maturation factor gamma, Gmfg, MGC126867, gamma |
| Swissprot | |
| Calculated MW | 17 kDa |
| Cellular Localization | Extracellular region or secreted, extracellular region, Other locations: ficolin-1-rich granule lumen, secretory granule lumen. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Glia maturation factor, gamma, also known as GMFG, is a 142 amino acid protein that belongs to the GMF subfamily of the larger actin-binding protein ADF family. GMF-gamma is expressed predominantly in lung, heart and placenta. GMF-gamma is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-gamma is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-gamma expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of actin-based cellular functions, GMF-gamma may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-gamma is primarily found in proliferative and differentiative organs. |
Other Clones
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Other Formats
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Unconjugated
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