Purified Anti-Mouse CD122 Antibody[TM-Beta 1] (AN004180P)
![Purified Anti-Mouse CD122 Antibody[TM-Beta 1] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: Unconjugated
APC Elab Fluor®488 Elab Fluor®647 Elab Fluor®Violet 450 FITC None (AF/LE) PE PE/Cyanine 5 PE/Cyanine 7 PerCP/Cyanine 5.5 Unconjugated Show More
| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Isotype | Rat IgG2b, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse CD122 protein |
| Abbre | CD122 |
| Synonyms | IL15RB, Interleukin-15 receptor subunit beta, p75, CD122, High affinity IL-2 receptor subunit beta, IL15Rbeta, IL-15Rbeta, IL-2 receptor subunit beta, Il-2/15Rbeta, IL-2R subunit beta, IL-2RB, Il-2Rbeta, Interleukin-2 receptor subunit beta, p70, p70-75, Il2rb, IL-2R&, beta |
| Swissprot | |
| Cellular Localization | Cell membrane, Cell surface |
| Tissue Specificity | Expressed in peripheral lymph node and 57 other cell types or tissues. |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Purification Method | >98%, Protein A/G purified |
| Clone No. | TM-Beta 1 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The TM-β1 antibody does inhibit IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis. |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| E-AB-F1029A | Purified Anti-Mouse CD122/IL-2RB Antibody[5H4] | 5H4 |
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