SARS-CoV-2 NSP3 Polyclonal Antibody(2019-nCoV) (E-AB-V1039)
For research use only.
Dilution | ELISA 1:4000-1:8000 |
Isotype | IgG |
Host | Rabbit |
Reactivity | SARS-COV2 |
Applications | ELISA |
Clonality | Polyclonal |
Immunogen | Recombinant SARS-CoV-2 NSP3 |
Synonyms | Non-structural protein 3, PL-PRO, PL2-PRO, Papain-like proteinase, Replicase polyprotein 1a |
Concentration | 0.33mg/ml |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF3. Prevents also host NF-kappa-B signaling. |
Other Clones
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HRP
Unconjugated
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