Immune checkpoints are regulators of immune activation, typically expressed on immune cells. They are key proteins that maintain the body's immune tolerance and regulate peripheral immune responses. Immune checkpoints can be divided into stimulatory and inhibitory types. Stimulatory immune checkpoints enhance the immune response against pathogens, while inhibitory immune checkpoints negatively regulate T cell activation. PD-1, PD-L1, CTLA-4, CD28, and OX40 are popular targets for cancer immunotherapy.
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                                                                                                Price: $438.00
                                                                                            
                                            
                                                    
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                                                                                                Price: $438.00
                                                                                            
                                        
                                                Cat. No.:
                                                
                                                
                                                    PKSH030444                                                
                                            
                                                                                        
                                                Expression Host:
                                                
                                                    HEK293 Cells                                                
                                            
                                                                                        
                                                Accession:
                                                
                                                    NP_054862.1                                                
                                            
                                                                                        
                                                Applications:
                                                
                                                    Cell culture                                                
                                            
                                                                                    
                                                                                                Price: $760.00
                                                                                            
                                            
                                                    
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                                                                                                Price: $760.00
                                                                                            
                                        
                                                Cat. No.:
                                                
                                                
                                                    PKSH031453                                                
                                            
                                                                                        
                                                Expression Host:
                                                
                                                    HEK293 Cells                                                
                                            
                                                                                        
                                                Accession:
                                                
                                                    Q7Z7D3-1                                                
                                            
                                                                                        
                                                Applications:
                                                
                                                    Cell culture                                                
                                            
                                                                                    
                                                                                                Price: $520.00
                                                                                            
                                            
                                                    
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                                                                                                Price: $520.00
                                                                                            
                                        
                                                Cat. No.:
                                                
                                                
                                                    PKSH032023                                                
                                            
                                                                                        
                                                Expression Host:
                                                
                                                    E.coli                                                
                                            
                                                                                        
                                                Accession:
                                                
                                                    P41273                                                
                                            
                                                                                        
                                                Applications:
                                                
                                                    Cell culture                                                
                                            
                                                                                    
                                                                                                Price: $520.00
                                                                                            
                                            
                                                    
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                                                                                                Price: $520.00
                                                                                            
                                        
                                                Cat. No.:
                                                
                                                
                                                    PKSH033725                                                
                                            
                                                                                        
                                                Expression Host:
                                                
                                                    E.coli                                                
                                            
                                                                                        
                                                Accession:
                                                
                                                    P29965                                                
                                            
                                                                                        
                                                Applications:
                                                
                                                    Cell culture                                                
                                            
                                                                                    
                                                                                                Price: $520.00
                                                                                            
                                            
                                                    
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                                                                                                Price: $520.00
                                                                                            
                                        
                                                Cat. No.:
                                                
                                                
                                                    PKSH034125                                                
                                            
                                                                                        
                                                Expression Host:
                                                
                                                    E.coli                                                
                                            
                                                                                        
                                                Accession:
                                                
                                                    O43557-2                                                
                                            
                                                                                        
                                                Applications:
                                                
                                                    Cell culture                                                
                                            
                                                                                    
                                                                                                Price: $520.00
                                                                                            
                                            
                                                    
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                                                                                                Price: $520.00
                                                                                            
                                        
                                                Cat. No.:
                                                
                                                
                                                    PKSH034127                                                
                                            
                                                                                        
                                                Expression Host:
                                                
                                                    E.coli                                                
                                            
                                                                                        
                                                Accession:
                                                
                                                    O95150                                                
                                            
                                                                                        
                                                Applications:
                                                
                                                    Cell culture                                                
                                            
                                                                                    
                                                                                                Price: $520.00
                                                                                            
                                            
                                                    
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                                                                                                Price: $520.00
                                                                                            
                                        
                                                Cat. No.:
                                                
                                                
                                                    PKSH034185                                                
                                            
                                                                                        
                                                Expression Host:
                                                
                                                    E.coli                                                
                                            
                                                                                        
                                                Accession:
                                                
                                                    O00182-2                                                
                                            
                                                                                        
                                                Applications:
                                                
                                                    Cell culture                                                
                                            
                                                                                    
                                                                                                Price: $520.00
                                                                                            
                                            
                                                    
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                                                                                                Price: $520.00
                                                                                            
                                        
                                                Cat. No.:
                                                
                                                
                                                    PKSM041487                                                
                                            
                                                                                        
                                                Expression Host:
                                                
                                                    E.coli                                                
                                            
                                                                                        
                                                Accession:
                                                
                                                    Q9QYH9                                                
                                            
                                                                                        
                                                Applications:
                                                
                                                    Cell culture                                                
                                            
                                                                                    
                                                                                                Price: $520.00
                                                                                            
                                            
                                                    
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                                                                                                Price: $520.00
                                                                                            
                                        
                                                Cat. No.:
                                                
                                                
                                                    PKSM041488                                                
                                            
                                                                                        
                                                Expression Host:
                                                
                                                    E.coli                                                
                                            
                                                                                        
                                                Accession:
                                                
                                                    P43488                                                
                                            
                                                                                        
                                                Applications:
                                                
                                                    Cell culture                                                
                                            
                                                                                    
                                                                                                Price: $198.00
                                                                                            
                                            
                                                    
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                                                                                                Price: $198.00
                                                                                            
                                        
                                                Cat. No.:
                                                
                                                
                                                    PKSQ050093                                                
                                            
                                                                                        
                                                Expression Host:
                                                
                                                    P.Pichia                                                
                                            
                                                                                        
                                                Accession:
                                                
                                                    H0VUB1                                                
                                            
                                                                                        
                                                Applications:
                                                
                                                    Cell culture                                                
                                            
                                                                                    
                            
