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Recombinant Human MAA/GSTZ1 Protein (His Tag) (PKSH032732)

All Size Price Qty
50μg $ 593.00
10μg $ 223.00
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For research use only.

Synonyms GSTZ1, GSTZ1-1, Glutathione S-Transferase Zeta 1, MAAI, Maleylacetoacetate Isomerase
Species Human
Expression Host E.coli
Sequence Met 1-Ala216
Accession O43708
Calculated Molecular Weight 25.2 kDa
Observed Molecular Weight 25-30 kDa
Tag C-His
Bio-activity Not validated for activity
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 1mM DTT, pH 8.0.
Reconstitution Not Applicable
Background Maleylacetoacetate Isomerase (MAAI) belongs to the Glutathione S-Transferase super-family. MAAI encodes multifunctional enzymes in the detoxification of electrophilic molecules by conjugation with glutathione, for example, mutagens, carcinogens and several therapeutic drugs. MAAI is a bifunctional protein with low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. MAAI can catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. But it has minimal glutathione-conjugating activity with 7-chloro-4-nitrobenz-2-oxa-1, ethacrynic acid 3-diazole and maleylacetoacetate isomerase activity.
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