Stem cells are a class of undifferentiated cells. They possess the ability of long-term self-renewal and can differentiate into specialized cells. Embryonic stem cells and adult stem cells make up the two main types of stem cells in mammals. Both types of stem cells have the same capacity to differentiate into different cell types, such as blood, heart, bones, skin, muscles, brain etc. Their ability of stimulating the body to repair itself make them be used to treat disease and injury.
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TGF-β signaling pathways are involved in many cellular processes in mature organisms and in developing embryos including cell growth, cell differentiation, apoptosis, and cell homeostasis.