Dear Partners, Distributors, and Valued Customers,
Elabscience® extends sincere gratitude for your long-standing trust and support. To further enhance product quality and technological competitiveness, and in response to the growing global demand for high-performance antibody reagents, Elabscience® has remained committed to innovation and breakthroughs in antibody R&D technology since its establishment.
With the rapid advancement of recombinant antibody technology, its recognized advantages in specificity, batch-to-batch consistency, production efficiency and application stability have become industry consensus. To provide our customers with superior products and services, We have launched a plan to introduce recombinant rabbit monoclonal antibodies due to their significant advantages in specificity, reproducibility, and stability.
Core Aspects of the Technology Upgrade
(I) Advantages of the Recombinant Rabbit Monoclonal Antibody Technology Platform
1. Molecular Design Level
a. Utilizes humanized framework with rabbit variable region recombinant technology, effectively reducing heterologous immunogenicity, ideal for long-term animal studies.
b. Integrate phage display library screening with epitope prediction algorithms, enabling the design of high-affinity antibodies (KD values typically < 10⁻⁹ M) against conformational antigens (e.g., GPCRs, ion channels).
2. Production Process Innovation
a. Employs CHO-S suspension cell culture in serum-free media, achieving batch yields exceeding 500mg, improving production efficiency by 20-fold compared with hybridoma technology.
b. Adopts continuous flow chromatography purification, ensuring endotoxin level < 0.1 EU/mg, and meeting stringent standards for preclinical research.
(II) Quality Control Standards
1. Implements accelerated stability testing (activity retention rate > 90% after 14 days at 37℃).
2. All batches undergo LC-MS peptide mapping and SEC-HPLC purity testing (monomer content ≥ 98%).
Performance Comparison for Replacement Products (Using Popular Targets as Examples)
|
Product Type |
Rabbit Polyclonal (Old) |
Recombinant Rabbit Monoclonal (New) |
|
Anti-β-actin Antibody |
Inter-batch CV 12-15% |
Inter-batch CV < 3% |
|
Anti-PD-1 Antibody |
WB detection requires 1:500 dilution |
WB detection possible at up to 1:5000 dilution |
|
Anti-GFAP Antibody |
Supports IHC application only |
Compatible with IHC/ICC/IF multiple scenarios |
We will provide real-time updates on the technology upgrade and the launch of recombinant rabbit monoclonal antibody products through our official website (www.elabscience.com) and email notifications. Should you have any questions, please contact us:
Toll-free: 1-888-852-8623
Tel: 1-832-243-6086
Add: 14780 Memorial Drive, Suite 105, Houston, Texas, 77079, USA
Email: orders@elabscience.com techsupport@elabscience.com
Thank you once again for your understanding and support. We remain committed to reciprocating your trust with higher quality products and services.
Hereby Announced
Jointly Issued by the R&D Center & Global Sales Department
November 10, 2025
