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Anti-Human CD3-APC/CD4-FITC/CD8a-PerCP-Cyanine5.5 Cocktail

Cat:E-AB-FC0002 Citations (1)
Manual MSDS

Price: $ 235

Price: $ 95

Price: $ 399

Size:
100Tests 20Tests 100Tests×2
Quantity:
  • Applications: FCM
  • Reactivity: Human
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Product Details
Background This product is a FCM antibody cocktail made up of APC Anti-Human CD3 Antibody [Clone: OKT-3] (Mouse IgG2a, κ), FITC Anti-Human CD4 Antibody [Clone: RPA-T4] (Mouse IgG1, κ) and PerCP/Cyanine5.5 Anti-Human CD8a Antibody [Clone: OKT-8] (Mouse IgG2a, κ).; CD3 is a heterotetrameric protein consisting of a CD3γ, a CDδ and 2 CD3ε. It forms complex with TCR. OKT-3 recognize human CD3ε. Human CD3 is expressed on the surface of T cells and NKT cells.; CD4 is also called Leu-3 or T4. It's a single-chain type I transmembrane glycoprotein, mainly expressed on the surface of T cells, and monocytes/macrophages. In T cells, CD4 forms complex with TCR/CD3 and play important roles in T cell immunity. The target of HIV is CD4+ T cells. Reduction of CD4+ T cells is the main reason of defected immunity after HIV infection.; CD8 is mainly expressed on cytotoxic T cells and also some subpopulations of NK cells. CD8 forms dimer function. In most cells, CD8 is a heterodimer consisting of CD8a and CD8b, but in NK cells nearly all CD8 is homodimer of CD8a. CD8a can form co-receptor with MHC-I restricted TCR to promote T cell antigen recognition and activation.
Clone No
Application
FCM
Reactivity Human
Form Liquid
Conjugation
APC;FITC;PerCP/Cyanine 5.5;
Conjugation information APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).
Spectrum
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date 12 months
Shipping Ice bag