Alternate Names	Interleukin-7 receptor subunit alpha,Il7r,IL-7 receptor subunit alpha,IL-7R subunit alpha,IL-7R-alpha,IL-7RA,CD127
Swissprot	P16872
References	1. Sudo T, et al. 1993. P. Natl. Acad. Sci. USA 90:9125. 2. Okuno Y, et al. 2001. P. Natl. Acad. Sci. USA 99:6246. 3. Pillai M, et al. 2004. Leukemia Lymphoma 45:2403.

Product Details

Form	Liquid
Clone No.	A7R34(See Other Available Formats)
Host	Rat
Isotype	Rat IgG2a, κ
Isotype Control	Biotin Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F09833B]
Reactivity	Mouse
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	Biotin

How to select the appropriate detection channel through the spectrogram?

Background

CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
FITC Anti-Mouse CD127/IL-7RA Antibody[A7R34]	50Tests, 100Tests, 100Tests×2	Check More
PE Anti-Mouse CD127/IL-7RA Antibody[A7R34]	50Tests, 100Tests, 100Tests×2	Check More
APC Anti-Mouse CD127/IL-7RA Antibody[A7R34]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5 Anti-Mouse CD127/IL-7RA Antibody[A7R34]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine7 Anti-Mouse CD127/IL-7RA Antibody[A7R34]	50Tests, 100Tests, 100Tests×2	Check More
PerCP/Cyanine5.5 Anti-Mouse CD127/IL-7RA Antibody[A7R34]	50Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 488 Anti-Mouse CD127/IL-7RA Antibody[A7R34]	50Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 647 Anti-Mouse CD127/IL-7RA Antibody[A7R34]	50Tests, 100Tests, 100Tests×2	Check More
FITC Anti-Mouse CD127/IL-7RA Antibody[A7R34]	25μg, 100μg	Check More
PE Anti-Mouse CD127/IL-7RA Antibody[A7R34]	25μg, 100μg	Check More
APC Anti-Mouse CD127/IL-7RA Antibody[A7R34]	25μg, 100μg	Check More
PE/Cyanine5 Anti-Mouse CD127/IL-7RA Antibody[A7R34]	25μg, 100μg	Check More
PE/Cyanine7 Anti-Mouse CD127/IL-7RA Antibody[A7R34]	25μg, 100μg	Check More
PerCP/Cyanine5.5 Anti-Mouse CD127/IL-7RA Antibody[A7R34]	25μg, 100μg	Check More
Elab Fluor^® 488 Anti-Mouse CD127/IL-7RA Antibody[A7R34]	25μg, 100μg	Check More
Elab Fluor^® 647 Anti-Mouse CD127/IL-7RA Antibody[A7R34]	25μg, 100μg	Check More

Citations

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