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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human breast cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human KRT8
Abbre CK-8
Synonyms CARD2,  CK 8,  CK-8,  CK8,  CYK8,  CYKER,  Cytokeratin endo A,  Cytokeratin-8,  DreK8,  EndoA,  K2C8,  K8,  KO,  KRT8,  Keratin,  Keratin 8,  Keratin type II cytoskeletal 8,  Keratin-8,  Krt 2.8,  MGC118110,  MGC174782,  MGC53564,  MGC85764,  Type-II keratin Kb8,  sb:cb186,  type II cytoskeletal 8
Swissprot
Cellular Localization Cytoplasm
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
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Unconjugated

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