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FITC Anti-Human/Mouse CD44 Antibody[IM7]

  • Cat.No.:E-AB-F1100UC

  • Applications: FCM
  • Isotype: Rat IgG2b, κ
  • Host: Rat

To Purchase E-AB-F1100UC

Size:
  • 25μg
  • 100μg
Price: $25
Qty:

Antigen Details

Alternate Names CD44 antigen,CD44,CDw44,Epican,Phagocytic glycoprotein 1,PGP-1,Phagocytic glycoprotein I,PGP-I,CD44,LHR, MDU2, MDU3, MIC4
Swissprot P15379,P16070
References
1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Haynes BF, et al. 1991. Cancer Cells 3:347.
3. Goldstein LA, et al. 1989. Cell 56:1063.
4. Mikecz K, et al. 1995. Nat. Med. 1:558.
5. Hegde V, et al. 2008. J. Leukocyte Biol. 84:134.
6. Liu T, et al. 2009. Biol. Direct 4:40.

Product Details

Form Liquid
Clone No. IM7
Host Rat
Isotype Rat IgG2b, κ
Isotype Control FITC Rat IgG2b, κ Isotype Control[LTF-2] [Product E-AB-F09843C]
Reactivity Human,Mouse
Application FCM
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation FITC
FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).


How to select the appropriate detection channel through the spectrogram?

Background

CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Product Name Sizes Price
AF/LE Purified Anti-Human/Mouse CD44 Antibody[IM7] 50μg, 500μg, 1mg Check More
Purified Anti-Human/Mouse CD44 Antibody[IM7] 25μg, 100μg Check More
Biotin Anti-Human/Mouse CD44 Antibody[IM7] 25μg, 100μg Check More
FITC Anti-Human/Mouse CD44 Antibody[IM7] 20Tests, 100Tests, 100Tests×2 Check More
PE Anti-Human/Mouse CD44 Antibody[IM7] 20Tests, 100Tests, 100Tests×2 Check More
APC Anti-Human/Mouse CD44 Antibody[IM7] 20Tests, 100Tests, 100Tests×2 Check More
PE/Cyanine5 Anti-Human/Mouse CD44 Antibody[IM7] 20Tests, 100Tests, 100Tests×2 Check More
PE/Cyanine7 Anti-Human/Mouse CD44 Antibody[IM7] 20Tests, 100Tests, 100Tests×2 Check More
PE/Cyanine5.5 Anti-Human/Mouse CD44 Antibody[IM7] 20Tests, 100Tests, 100Tests×2 Check More
PerCP/Cyanine5.5 Anti-Human/Mouse CD44 Antibody[IM7] 20Tests, 100Tests, 100Tests×2 Check More
Elab Fluor® 488 Anti-Human/Mouse CD44 Antibody[IM7] 20Tests, 100Tests, 100Tests×2 Check More
Elab Fluor® 647 Anti-Human/Mouse CD44 Antibody[IM7] 20Tests, 100Tests, 100Tests×2 Check More
Elab Fluor® Violet 450 Anti-Human/Mouse CD44 Antibody[IM7] 20Tests, 100Tests, 100Tests×2 Check More
Elab Fluor® Red 780 Anti-Human/Mouse CD44 Antibody[IM7] 20Tests, 100Tests, 100Tests×2 Check More
PE Anti-Human/Mouse CD44 Antibody[IM7] 25μg, 100μg Check More
APC Anti-Human/Mouse CD44 Antibody[IM7] 25μg, 100μg Check More
PE/Cyanine5 Anti-Human/Mouse CD44 Antibody[IM7] 25μg, 100μg Check More
PE/Cyanine7 Anti-Human/Mouse CD44 Antibody[IM7] 25μg, 100μg Check More
PE/Cyanine5.5 Anti-Human/Mouse CD44 Antibody[IM7] 25μg, 100μg Check More
PerCP/Cyanine5.5 Anti-Human/Mouse CD44 Antibody[IM7] 25μg, 100μg Check More
Elab Fluor® 488 Anti-Human/Mouse CD44 Antibody[IM7] 25μg, 100μg Check More
Elab Fluor® 647 Anti-Human/Mouse CD44 Antibody[IM7] 25μg, 100μg Check More
Elab Fluor® Violet 450 Anti-Human/Mouse CD44 Antibody[IM7] 25μg, 100μg Check More
Elab Fluor® Red 780 Anti-Human/Mouse CD44 Antibody[IM7] 25μg, 100μg Check More

Citations

  1. Biomaterials Science (2019) IF: 5.251
    Targeted co-delivery of the aldose reductase inhibitor epalrestat and chemotherapeutic doxorubicin via a redox-sensitive prodrug approach promotes synergistic tumor suppression

    DOI: 10.1039/C9BM00221A

    Sample: Mda-Mb-231 Cells
  2. MOLECULAR PHARMACEUTICS (2023) IF: 5.364
    Self-Assembled Redox-Sensitive Polymeric Nanostructures Facilitate the Intracellular Delivery of Paclitaxel for Improved Breast Cancer Therapy

    DOI: 10.1021/acs.molpharmaceut.2c00673

    Sample: Mda-Mb-231 Cell
  3. BIOMACROMOLECULES (2022) IF: 6.988
    Amalgamated Microneedle Array Bearing Ribociclib-Loaded Transfersomes Eradicates Breast Cancer via CD44 Targeting

    DOI: 10.1021/acs.biomac.1c01076

    PMID: 34978424

    Sample: La-7 Cell,Mda-Mb 231 Cell
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