FOLR1 Polyclonal Antibody (E-AB-19878)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human tonsil |
| Dilution | IHC 1:40-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human FOLR1 |
| Abbre | FOLR1 |
| Synonyms | Adult folate binding protein, Adult folate-binding protein, FBP, FOLR, FOLR1, FR alpha, FR-alpha, FRalpha, Folate Receptor 1 Adult, Folate Receptor 1 Precursor, Folate receptor, Folate receptor 1, Folate receptor adult, Folate receptor alpha, KB cells FBP, M, adult |
| Swissprot | |
| Cellular Localization | Cell membrane. Secreted. |
| Concentration | 2.28 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Tags and Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Folate receptor 1 (FOLR1),also known as folate receptor alpha or adult folate-binding protein (FBP),is a 38-kDa glycoprotein belonging to the folate receptor family . The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung,kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer,non-small cell lung cancer,breast cancer,kidney cancer and high-grade osteosarcoma . |
Other Clones
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Other Formats
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Unconjugated
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