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For research use only.

Verified Samples Verified Samples in IHC: Rat brain, Human liver damage
Verified Samples in IF: C6, NIH/3T3, U-2OS
Dilution IHC 1:50-1:200,  IF 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC,  IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of mouse FoxO3a (NP_062714.1).
Abbre FoxO3a
Synonyms AF6q21,  FKHRL1,  FKHRL1P2,  FOXO2,  FOXO3,  FOXO3A
Swissprot
Cellular Localization Cytoplasm>cytosol. Nucleus. Translocates to the nucleus upon oxidative stress and in the absence of survival factors.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
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Unconjugated

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