HP Polyclonal Antibody

Uniprot : P00738
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14133

      Synonyms:Binding peptide,BP,Haptoglobin alpha chain,Haptoglobin alpha(1S) beta,Haptoglobin alpha(2FS) beta,Haptoglobin beta chain,Haptoglobin,alpha polypeptide,Haptoglobin,beta polypeptide,HP,HP2 ALPHA2,HP2ALPHA2,HPA1S,HPT,HPT,MGC111141,Zonulin

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Binding peptide,BP,Haptoglobin alpha chain,Haptoglobin alpha(1S) beta,Haptoglobin alpha(2FS) beta,Haptoglobin beta chain,Haptoglobin,alpha polypeptide,Haptoglobin,beta polypeptide,HP,HP2 ALPHA2,HP2ALPHA2,HPA1S,HPT,HPT,MGC111141,Zonulin
      Swissprot P00738
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human HP
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:200-1:1000
      Concentration 0.4 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted.
      Tissue specificity Expressed by the liver and secreted in plasma.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.

      Images

      Western Blot analysis of Human brain gliomas tissue using HP Polyclonal Antibody at dilution of 1:400

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      MSDS for ELISA

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