IKZF3 Polyclonal Antibody

Uniprot : Q9UKT9
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14763

      Synonyms:AIO,Aiolos,IKAROS family zinc finger 3 (Aiolos),IKAROS family zinc finger 3,Ikaros family zinc finger protein 3,IKZF 3,IKZF3,IKZF3,zinc finger DNA binding protein Aiolos,Zinc finger protein Aiolos,Zinc finger protein subfamily 1A 3 (Aiolos),Zinc finger protein subfamily 1A 3,Zinc finger protein subfamily 1A,member 3,ZNFN1A3

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms AIO,Aiolos,IKAROS family zinc finger 3 (Aiolos),IKAROS family zinc finger 3,Ikaros family zinc finger protein 3,IKZF 3,IKZF3,IKZF3,zinc finger DNA binding protein Aiolos,Zinc finger protein Aiolos,Zinc finger protein subfamily 1A 3 (Aiolos),Zinc finger protein subfamily 1A 3,Zinc finger protein subfamily 1A,member 3,ZNFN1A3
      Swissprot Q9UKT9
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human IKZF3
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 1.6 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus. Cytoplasm.
      Tissue specificity Expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using IKZF3 Polyclonal Antibody at dilution 1:60

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using IKZF3 Polyclonal Antibody at dilution 1:60

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