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IKZF3 Polyclonal Antibody

Uniprot : Q9UKT9

Catalog number:E-AB-14763

Synonyms:AIO,Aiolos,IKAROS family zinc finger 3 (Aiolos),IKAROS family zinc finger 3,Ikaros family zinc finger protein 3,IKZF 3,IKZF3,IKZF3,zinc finger DNA binding protein Aiolos,Zinc finger protein Aiolos,Zinc finger protein subfamily 1A 3 (Aiolos),Zinc finger protein subfamily 1A 3,Zinc finger protein subfamily 1A,member 3,ZNFN1A3

Size:

20μL
60μL
120μL
200μL

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Price: $69

Host: Rabbit

Reactivity: H,M

Applications: IHC,ELISA

Lead Time: 7~10 daysWelcome to order from local distributors.

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Overview

Synonyms	AIO,Aiolos,IKAROS family zinc finger 3 (Aiolos),IKAROS family zinc finger 3,Ikaros family zinc finger protein 3,IKZF 3,IKZF3,IKZF3,zinc finger DNA binding protein Aiolos,Zinc finger protein Aiolos,Zinc finger protein subfamily 1A 3 (Aiolos),Zinc finger protein subfamily 1A 3,Zinc finger protein subfamily 1A,member 3,ZNFN1A3
Swissprot	Q9UKT9
Source	Rabbit
Reactivity	Human,Mouse
Immunogen	Recombinant protein of human IKZF3
Application	IHC(Detection kit: E-IR-R213),ELISA
Recommended dilution	IHC 1:50-1:200
Concentration	1.6 mg/mL
Clonality	Polyclonal

Properties

Cellular localization	Nucleus. Cytoplasm.
Tissue specificity	Expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus.
Isotype	IgG
Purification	Affinity purification
Conjugation	Unconjugated
Storage instructions	Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Background	This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.