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Catalog number:E-AB-14763
Synonyms:AIO,Aiolos,IKAROS family zinc finger 3 (Aiolos),IKAROS family zinc finger 3,Ikaros family zinc finger protein 3,IKZF 3,IKZF3,IKZF3,zinc finger DNA binding protein Aiolos,Zinc finger protein Aiolos,Zinc finger protein subfamily 1A 3 (Aiolos),Zinc finger protein subfamily 1A 3,Zinc finger protein subfamily 1A,member 3,ZNFN1A3
Host: Rabbit
Reactivity: H,M
Applications: IHC,ELISA
Lead Time: 7~10 daysWelcome to order from local distributors.
Add to cart Compare Bulk request ManualSynonyms | AIO,Aiolos,IKAROS family zinc finger 3 (Aiolos),IKAROS family zinc finger 3,Ikaros family zinc finger protein 3,IKZF 3,IKZF3,IKZF3,zinc finger DNA binding protein Aiolos,Zinc finger protein Aiolos,Zinc finger protein subfamily 1A 3 (Aiolos),Zinc finger protein subfamily 1A 3,Zinc finger protein subfamily 1A,member 3,ZNFN1A3 |
Swissprot | Q9UKT9 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Recombinant protein of human IKZF3 |
Application | IHC(Detection kit: E-IR-R213),ELISA |
Recommended dilution | IHC 1:50-1:200 |
Concentration | 1.6 mg/mL |
Clonality | Polyclonal |
Cellular localization | Nucleus. Cytoplasm. |
Tissue specificity | Expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Background | This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. |