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LRP5 Polyclonal Antibody (E-AB-12546)

All Size Price Qty
200μL $ 399.00
120μL $ 240.00
60μL $ 143.00
20μL $ 73.00
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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer, Human ovarian cancer
Dilution IHC 1:50-1:200
Clonality Polyclonal
Immunogen Synthetic peptide of human LRP5
Abbre LRP5
Synonyms BMND1,  EVR1,  EVR4,  HBM,  LR3,  LRP-5,  LRP5,  LRP7,  Low density lipoprotein receptor related protein 5,  Low density lipoprotein receptor related protein 7,  Low-density lipoprotein receptor-related protein 5,  Lrp5,  OPPG,  OPS,  OPTA1,  Osteoporosis pseudoglioma syndrome,  VBCH2
Swissprot
Cellular Localization Membrane. Endoplasmic reticulum. Chaperoned to the plasma membrane by MESD.
Concentration 0.6 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Neuroscience,  Signal Transduction,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
Other Clones

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Unconjugated

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