MPO Polyclonal Antibody

Uniprot : P05164,P11247
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      Catalog number:E-AB-70091

      Synonyms:84 kDa myeloperoxidase,89 kDa myeloperoxidase,EC 1.11.1.7,EC1.11.2.2,fj80f04,MPO,mpx,myeloid-specific peroxidase,Myeloperoxidase,Myeloperoxidase heavy chain,Myeloperoxidase light chain,PERM,wu:fj80f04

      Size:
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $129

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,IF

      Lead Time: 7-10daysWelcome to order from local distributors.

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      Overview

      Synonyms 84 kDa myeloperoxidase,89 kDa myeloperoxidase,EC 1.11.1.7,EC1.11.2.2,fj80f04,MPO,mpx,myeloid-specific peroxidase,Myeloperoxidase,Myeloperoxidase heavy chain,Myeloperoxidase light chain,PERM,wu:fj80f04
      Swissprot P05164,P11247
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen KLH conjugated Synthetic peptide corresponding to Mouse MPO
      Application IHC(Detection kit: E-IR-R213),IF
      Recommended dilution IHC 1:500-1:1000, IF 1:200-1:500
      Concentration 0.81 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Lysosome
      Tissue specificity Highest expression level in bone marrow cell
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
      Background Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. 

      Images

      Immunohistochemistry analysis of paraffin-embedded human liver using MPO Polyclonal Antibody at dilution of 1:300.

      Immunohistochemistry analysis of paraffin-embedded mouse bone using MPO Polyclonal Antibody at dilution of 1:300.

      Immunofluorescence analysis of paraffin-embedded human liver using MPO Polyclonal Antibody at dilution of 1:300.

      Immunohistochemistry analysis of paraffin-embedded Human Spleen using MPO Polyclonal Antibody(Detected by Lifespan)

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