Alternate Names	Integrin alpha-Iib,ITGA2B,GPalpha Iib,GPIIb,Platelet membrane glycoprotein Iib,CD41,GP2B, ITGAB
Swissprot	P08514
References	1. Denzin L, et al. 1996. J. Exp. Med. 184:2153. 2. Denzin L, et al. 1995. Cell 82:155. 3. Riberdy J, et al. 1994. J. Cell Biol. 125:1225.

Product Details

Form	Liquid
Clone No.	HIP8
Host	Mouse
Isotype	Mouse IgG1, κ
Isotype Control	PE Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792D]
Reactivity	Human
Application	FCM
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	PE
	PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).

How to select the appropriate detection channel through the spectrogram?

Background

CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
Biotin Anti-Human CD41 Antibody[HIP8]	25μg, 100μg	Check More
FITC Anti-Human CD41 Antibody[HIP8]	20Tests, 100Tests, 100Tests×2	Check More
APC Anti-Human CD41 Antibody[HIP8]	20Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5 Anti-Human CD41 Antibody[HIP8]	20Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine7 Anti-Human CD41 Antibody[HIP8]	20Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5.5 Anti-Human CD41 Antibody[HIP8]	20Tests, 100Tests, 100Tests×2	Check More
PerCP/Cyanine5.5 Anti-Human CD41 Antibody[HIP8]	20Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 488 Anti-Human CD41 Antibody[HIP8]	20Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 647 Anti-Human CD41 Antibody[HIP8]	20Tests, 100Tests, 100Tests×2	Check More

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