For research use only.
| Background | CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Alternate Names | Activation B7-2 antigen, Cd86, ETC-1, Early T-cell costimulatory molecule 1, T-lymphocyte activation antigen CD86 |
| Swissprot | |
| Clone No | |
| Host | Mouse |
| Reactivity | Human |
| Isotype | Mouse IgG1, κ |
| Isotype Control | |
| Application |
FCM
|
| Form | Liquid |
| Conjugation | PE |
| Conjugation information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration date | 12 months |
| Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®488
Elab Fluor®647
Elab Fluor®Red 780
Elab Fluor®Violet 610
FITC
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP/Cyanine 5.5
Unconjugated
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