PE/Cyanine5.5 Anti-Mouse CD279/PD-1 Antibody[29F.1A12] (E-AB-F1131I)
For research use only.
| Alternate Names | Programmed Death-1, PD-1 |
| Clone No | |
| Leadtime | Order now, ship in 3 days |
| Background | CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts. |
| Abbre | CD279 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype | Rat IgG2a, κ |
| Isotype Control | E-AB-F09832I |
| Applications |
FCM
|
| Research Areas | Cancer Biomarkers;Immunology;Inhibitory Molecules |
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
5 μL/Test
|
| Conjugation | PE/Cyanine 5.5 |
| Conjugation Information | PE/Cyanine5.5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 690 nm (e.g., a 690/50 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®647
Elab Fluor®700
Elab Fluor®Red 780
FITC
None (AF/LE)
PE
PE/Cyanine 5.5
PE/Cyanine 7
PerCP/Cyanine 5.5
Unconjugated
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