PGR Polyclonal Antibody (E-AB-64004)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human uterus |
| Dilution | IHC 1:50-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human PGR (NP_000917.3). |
| Abbre | PGR |
| Synonyms | NR3C3, PGR, PR |
| Swissprot | |
| Cellular Localization | Nucleus, Cytoplasm, Nucleoplasmic shuttling is both homone- and cell cycle-dependent, On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases, Mitochondrion outer membrane and Nucleus, Cytoplasm, Mainly nuclear. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. |
Other Clones
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Other Formats
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Unconjugated
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